Spiro

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(@theresem)
Active Member     United States of America, Minnesota
Joined: 5 years ago

I hope this is the right place for this question. Sorry if it's not.

Has anyone had ...or maybe I should ask it like this.

What are your thoughts and experiences on Spiro?

I read an article which scared me a bit.

https://moderntranshormones.com/2018/01/01/whats-wrong-with-spironolactone/

Therese

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(@keriw)
New Member     United States of America, North Carolina
Joined: 5 years ago

I think its a good medication. It has lowered my T levels, and I have experienced the side effects that come with lower T level while on it.

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Posts: 25
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(@tracyorisittraci)
Eminent Member     United States of America, Texas, Austin
Joined: 5 years ago

My personal experience with spiroloctone is positive. Within 2 months my testosterone levels went from 823 pre hrt level. 2 months later my testosterone is less than 12 and has stayed there for the last 3 months. My estrogen levels have been climbing since the start of hrt, but not at the levels theu should be, however my endo wants to up my dose and switch me to estriadial injectables which generally have a better success rate. Hope that helped, the only side effect is lactic acid buildup in my calves. So had to reduce my pottasium intake to avoid cramps in the calves. Good luck!

Traci

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(@meran)
Eminent Member     United States of America, Tennessee, Nashville
Joined: 5 years ago

I had the same effects as Traci Lynn wrote about.  My Endo said my T level was higher than most men, that most men would dream of having, around 740.  But shortly after starting Spiro, it was less then 100.  Then a month later, it was down to  9!  Then I was started on Estradiol.  The first thing I noticed with such a low T level was no more morning wood!  In the months thereafter, my privates began shrinking.  I also noticed, I could not get an erection as easy as it used to be.  I could still orgasm, but I was 'shooting blanks'!   After a year of Spiro pills, the Endo gave me the 90-day shots in the abdomen.  I had those for about 1.5 yrs.  Then I was put on 180-day shots and have been on them since.  What depressed me was they lowered my Estradiol dosage to .75 mg twice a week!   Since I was put that low, I have not noticed any new changes.  I started on 10mg/day, then down to 5, then down to 2, now .75 twice a week!  I know the Endo was worried about blood clotting, but never had that happen on higher doses.

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(@cloe-anne-webb)
Honorable Member     United States of America, Virginia, Fairfax
Joined: 6 years ago

It's good at lowering your T quick, but has problems long term such as brain fog and anxiety both of which I experienced. It creeps up on you too.

A high enough blood level of E will suppress the T on it's own. I switched endo's to a doc who shadowed Dr Powers and the first thing we did was cut the spiro out because the injections I had started a few months earlier gave me good levels to do that.

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(@krisfl)
Active Member     United States of America, Florida
Joined: 4 years ago

I just couldn’t do spiro. Brain fog and the excessive urinating. I’m on Dutesteride now, and it has down the same as it relates to t levels.

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(@dannilynn)
Active Member     United States of America, Kentucky, Louisville
Joined: 5 years ago

The only bad experience I've had with spiro is the frequent urinating. It caused my kidney function to be elevated and my doctor has taken me off of them for 2 weeks.

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(@Anonymous)
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It’s not necessary for all of us.  I purposely took EV injections only without Spiro to see what my body did with just that, blood levels- wise.  If it didn’t bring my T levels down,  then I would plan toconsider Spiro. As it carried more risks,  especially for someone like me that has kidney stones and dehydration issues in the past. In my case,  with the standard initial dosing for EV,  my T crashed out by itself to the bottom of female ranges by my first post-HRT blood test. I’ve since about halved my dose,  and nearly two years later,  I’ve never seen my T levels rise,  and E2 has been in “ideal” ranges.

IMHO,  start EV injections first,  see what your blood levels do,  and address with Spiro later, if you can’t get T down.  I had two different doctors,  both supporting this approach when I suggested it as risk avoidance.

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