Regarding full disclosure, I have not done HRT and have no plans to do so. If anyone wants to ask why, send me a PM and I will discuss it.
That said, as we know, there are trans people who do self-medication. The problem is monitoring. For example, I take an arthritis drug (one of the ones advertised on TV) that requires certain periodic blood tests so that something untoward doesn’t go undetected. It is a very important part of the treatment. Since the blood tests are established as a particular part of the Plume program, that is a positive to me.
One additional piece I will add is that a while back someone here asked if anyone was doing self-medication. I did a bit of searching and found (and posted) the recommended blood test protocols, and their frequency. for both trans men and trans women. I suggest doing the same research and compare that with the Plume information.