Reply To: Sublingual or Oral?

Emily Alt

I don’t have any experience with oral or sublingual estrogen. Mainly that’s because I’m prone to blood clots (genetic condition) and need to reduce my risk as much as possible. I inject estrogen subcutaneously instead. Injections and patches appear to have the lowest risk among the common delivery methods. Injections are also noted for their slower delivery of E. Peaks and troughs of E are minimized.

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